The Colorado Bureau of Investigation says a former DNA scientist cut corners and didn't follow standard testing protocols, raising questions about hundreds of criminal cases in which she processed evidence
/PRNewswire/ -- GenScript, a global leader in life science research and application services, is excited to announce that Dr. David R. Liu, a prominent figure...
Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Oklahoma State University have identified key genes and the mechanism by which they control flowering in sorghum, an important bioenergy crop. The findings, just published in the journal New Phytologist, suggest strategies to delay sorghum flowering to maximize plant growth and the amount of biomass available for generating biofuels and bioproducts.
Researchers have discovered that a specific genetic mutation causes the unique brown fur of Qinling pandas.
The company, which is currently in 'stealth mode', expects to double in size over the next two years
/PRNewswire/ -- Next generation genomic tools company, Nabsys, has executed a nonexclusive agreement with Canadian distributor, DMark Biosciences ("DMark"),...
The University of Aberdeen team hope their findings could improve the lives of anxiety patients.
Federal Reserve Chairman Jerome Powell says the central bank will likely start cutting interest rates this year. But he offered no firm timetable, saying the economic outlook is still uncertain.
Chinese researchers have found the gene responsible for brown fur seen in a tiny group of giant pandas instead of normal black fur.
The study also found that the same genetic mutation is present in two-thirds of flat-coated retrievers
In a groundbreaking study at Ume University in Sweden, researchers have identified a specific gene that could play a crucial role in developing new
"Random DNA" is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
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One of the most striking examples of gut plasticity can be observed in animals that are exposed to prolonged periods of fasting, such as hibernating animals or phyton snakes that goes for months without eating, where the gut shrinks with as much as 50%, but recovers in size following a few days of r
The team's lofty goal of "resurrection" is still far from reality, but scientists say the advancement in understanding cells could help with elephant conservation
When faced with a threat, T cells have the decision-making flexibility to both clear out the pathogen now and ready themselves for a future encounter.
When a child falls off her bike and scrapes her knee, skin stem cells rush to the rescue, growing new epidermis to cover the wound. But only some of the stem cells that will ultimately patch her up are normally dedicated to replenishing the epidermis that protects her body.
Queensland researchers have become the first in Australia to use human stem cells to generate fully functioning skin tissue in a laboratory, a significant step toward better treatments for severe burns and wounds.
A team of bioengineers at de-extinction company Colossal Biosciences has announced that they created induced pluripotent stem cells (iPSC) from elephant skin cells. In speaking with the press, officials with the team reported that they are still in the process of writing a paper describing their efforts and plan to post it on the bioRxiv preprint server. Ewen Callaway has published a News article in Nature about the announcement.
One step toward de-extincting a mammoth, one giant leap for elephant kind.
Scientists at the company Colossal Biosciences have derived induced pluripotent stem cells from elephants, which they say could boost efforts to resurrect woolly mammoths.
Stem cells are the body's wellspring of renewal. They can turn into any kind of cell the body needs, from liver to skin to bone. But the well would run dry if all the stem cells transformed.
Early experiences in an animal's life can have a significant impact on its capacity to thrive, even years or decades later, and DNA methylation may help record their effects.
One of the fundamental goals of basic biology is understanding how diverse cell types work in concert to form tissues, organs, and organ systems. Recent efforts to catalog the different cell types in every tissue in our bodies are a step in the right direction, but only one piece of the puzzle. The great mystery of how those cells communicate with one another remains unsolved.
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EurekaBio closed a $40M Series B+ funding to support the commercialization of its EuLV Lentiviral Vector Production System. Click here to read more.
Technique employs patient's own cells as a Trojan horse to deliver cancer-destroying medications directly to tumors. While lung cancer may not be the most common type of cancer, but it is by far the deadliest. Despite treatments such as surgery, radiation therapy, and chemotherapy, only about a
/PRNewswire/ -- Delcath Systems, Inc. (Nasdaq: DCTH), an interventional oncology company focused on the treatment of primary and metastatic cancers of the...
By leveraging the "brain center" of the immune response, Elicio's novel approach to cancer targeting and treatment holds the potential to transform the lives of patients with solid tumors.
An experimental Alzheimer's treatment involving sounds and flickering lights also prevented a decline in mental sharpness among mice having chemotherapy
/PRNewswire/ -- BioGate Precision Medicine Corp., a member of Powerchip Group, held a press conference today to unveil an innovative breakthrough in pancreatic...
/PRNewswire/ -- An interdisciplinary, global team of scientists led by Yael Moss, MD, Professor of Pediatrics in the Cancer Center at Children's Hospital of...
Camila Row, wife of Hallmark star Brennan Elliott, continues to battle stage 4 stomach cancer and shared an important update.
Updated preclinical data will be presented from Ryvu's synthetic lethality pipeline, including PRMT5 inhibitors in MTAP-Deficient cancers, WRN inhibitors for...
Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.
/PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced that preclinical data for agents targeting Nectin-4, KRAS G12D, and BRM (SMARCA2) will be...
/PRNewswire/ -- OncoHost, a technology company transforming the approach to precision medicine for improved patient outcomes, today announced it will be...
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Tests show the recombinant vaccine outperforming existing vaccines in some areas. Recombinant protein vaccines, like the Novavax vaccine used to fight COVID-19, offer several advantages over conventional vaccines. Theyre easy to precisely produce. Theyre safe, and potentially more effective.
Since its 1976 emergence in Africa, the Ebola virus has proven an especially lethal contagion, killing roughly 50% of the people who contract it. The 2019 FDA approval of a vaccine, combined with the subsequent development of two antibody-based drugs, marked unprecedented progress against one species of the virus. Yet the continuing threat posed by several other types of Ebola has left researchers in pursuit of additional treatmentsparticularly in developing regions of Africa, where limited infr
The new AI will be offered publicly to scientists so they can create novel interacting bio-components that could lead to new therapies.
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infectionsand, alas, extraordinarily difficult to target with drugs.
A recent discovery has found a direct link between the eye and the brain's immune response.
The virus's capsid functions as a molecular transporter. Every year, approximately one million people globally contract HIV, the virus responsible for AIDS. For the virus to multiply and propagate the infection, it must transport its genetic information into the nucleus of a cell and incorporate it
Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. These vaccines often include other molecules called adjuvants, which help to boost the immune system's response to the protein.
Researchers from the Bhogaraju Group at EMBL Grenoble have gained new insights into how a cancer-relevant family of proteins bind their targets. The results of the study, published in The EMBO Journal, could potentially help in the development of drugs against certain chemotherapy- and radiotherapy-resistant cancers.
An underexplored part of the flu viruses — the "dark side" of a specific protein — is likely a good target for universal flu vaccines.
Were still using century-old technology to make snake antivenom. A method fit for the 21st century is on the horizon.
Recent years have seen the rise of bacterial pathogens that have developed resistance to antibiotics. One such superbug, carbapenem-resistant Acinetobacter baumannii (CRAB), kills hundreds of critically ill patients in the U.S. each year, usually in hospital settings, by causing blood, lung, or urinary tract infections that don't respond to treatments.
Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal Nature Chemistry.
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/PRNewswire/ -- Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing medicines targeting metalloenzymes, today...
In a study recently published in the journal Small, researchers from Nano Life Science Institute (WPI NanoLSI), Kanazawa University, Japan, collaborating with Professor Sarikaya, Seattle, U.S., used frequency modulated atomic force microscopy to reveal the molecular architecture of genetically designed and point mutated peptides and their self-organizations each forming single-molecule thick, distinct biological crystals on atomically flat graphite and MoS2 surfaces, offering a potential platfor
The metabolic process of bilirubin has been a focus of medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown of aging or damaged red blood cells, and its effective removal is essential for human health.
For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example. One small protein in SARS-CoV-2, the membrane protein, or M protein, is the most abundant and plays a crucial role in how the virus acquires its spherical structure. Nonetheless, this protein's properties are not well understood.
Researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nature Communications that TMEM16F, a transmembrane protein that facilitates the passive movement of phospholipids and ions across membranes, explores a larger conformational landscape than previously thought in order to perform its unique functions.
Protease inhibitors are a promising strategy for enhancing herbivore resistance in plants, which is crucial for addressing the significant yield losses in crops such as tea plants due to insect herbivores. Serine protease inhibitors (SERPIN) are one of the largest superfamilies of protease inhibitors in plants and play a key role in defense against herbivores.
Many proteins within the body form complexes with other proteins, determining the fate of cells. Therefore, the analysis of protein-protein interactions (PPI) is a crucial process for understanding the biological function of target proteins.
Cells need energy to function. Researchers at the University of Gothenburg can now explain how energy is guided in the cell by small atomic movements to reach its destination in the protein. Imitating these structural changes of the proteins could lead to more efficient solar cells in the future.
Scientists at St. Jude Children's Research Hospital, collaborating internationally, used data science, pharmacology, and structural details to explore at the atomic level how each amino acid in the adrenaline-binding receptor affects its activity when interacting with this natural ligand. They di
Scientists have discovered a new, intermediate state in the process of protein folding, showing folding can occur in two stages, one fast and the next found to be much slower. The findings are published in the journal Physical Review Letters.
Cells need energy to function. Researchers at the University of Gothenburg can now explain how energy is guided in the cell by small atomic movements to reach its destination in the protein. Imitating these structural changes of the proteins could lead to more efficient solar cells in the future.
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptidesmolecules that hold promise in pharmaceuticals as they can bind to challenging drug targets.
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