Dominic Kpadeh heaves a hammer over his head to crack a half-tonne rock in a northern suburb of Liberia's capital Monrovia, knowing his hard labour earns him far less than a year ago. Stories such as Kpadeh's are common in Liberia, where rampant inflation has left many people struggling and
The studys critical take is at odds with the plaudits that drug-maker Merck and its partners in the international health community have received for getting an Ebola vaccine over the regulatory finish line
Comprehensive clinical testing led Children's Hospital Colorado researchers to connect enterovirus A71, which causes Hand, Foot and Mouth Disease, to outbreak of neurological illness. The Lancet Infectious Diseases recently published the results of an observational study led by researchers on Child
As the world's second-worst Ebola outbreak in history drags into a new year, experts think the solution is less about medicine, and more about security.
The United Nations agency said that a lack of funds and low routine vaccination coverage, as well as malnutrition, were inhibiting the response to save lives and control the outbreak in the country.
Opposition postpones anti-government rally in Liberia
The United Nations and other West African countries urged Liberia on Friday to avoid a major protest rally planned for next week as the impoverished country grapples with a deep economic crisis. The Economic Community of West African States (ECOWAS) and the UN's office in West Africa and the Sahel
Years of disabling PTSD followed Preston Gormans unlikely survival after he contracted the fearsome disease in Sierra Leone.
Congress must renew the Ebola response program.
Leading health experts shared the innovations and breakthroughs that they said saved millions of lives over the past ten years.
The owner of Sierra Leone's East End Tigers says Victoria Conteh is the top-flight's first woman coach 'because she's qualified and that's the bottom line'.
Conflict, insecurity, and a lack of access to patients are the principal factors slowing down efforts to ending the Ebola outbreak in...
/PRNewswire/ -- An article published in Experimental Biology and Medicine (Volume 244, Issue 18, December 2019...
A CALCR cell found in mice may stop feeding without subsequential nauseating effects, as well as influence the long term intake of food.
Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development.
New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer's disease, anxiety, and depression.
The study has identified a strategy that may support the regeneration of nerves affected by the injury.
The new study explores alpha-synuclein's basic properties, with a focus on a section of the protein known as the non-amyloidal component (NAC). The research was done on fruit fly larvae that were genetically engineered to produce both normal and mutated forms of human alpha-synuclein.
Researchers at the University of Malta have discovered a link between diverse genes whose mutation causes the debilitating and fatal human disease known as amyotrophic lateral sclerosis (ALS). Convergence in the molecular pathways underlying different ALS-causing genes points to potential new targets for drug development.
MDC researchers established a new model to study neuromuscular development and disorders. For the first time two distinct human tissues co-developed in the lab from one progenitor cell type and self-organized into a complex, functional neuromuscular organoid.
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency--a rare disorder first described in 2012--lack sufficient water channel proteins called aquaporins. The discovery was published in Cell Reports and may help explain the disorder's wide-ranging symptoms--including the inability to produce tears, seizures and developmental delays--and opens new avenues to find therapies to treat the disorder.
Biologists from The University of Manchester have explained for the first time why having a good night's sleep really could prepare us for the rigors of the day ahead. The study in mice and published in Nature Cell Biology, shows how the body clock mechanism boosts our ability to maintain our bod
What could this tell us about the aging process in humans?
Biologists explain for first time why having a good night's sleep really could prepare us for a busy day
Scientists have made a significant discovery about the genetic origins of how plants evolved from living in water to land 470 million years ago.
The long read: Gene and Sandy Ralston are a married couple in their 70s, who also happen to be among North Americas leading experts at searching for the dead
The debate about gene editing will help shape the future of the human race. But how should the discussion get started?
A new study from Washington University School of Medicine in St. Louis suggests that extremely rare, harmful genetic mutations present in healthy donors' stem cells -- though not causing health problems in the donors -- may be passed on to cancer patients receiving stem cell transplants, potentially creating health problems for the recipients. Among the concerns are heart damage, graft-versus-host disease and possible new leukemias.
Vague promises of gene therapies to come were part of the mystique of 23andMe
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assaults on disease. The DNA-binding editorial assistants were devised by a US-based team of bioengineers, who describe their design in APL Bioengineering.
/PRNewswire/ -- An incentive prize ten times the size of the Nobel believed to be the largest single award ever in basic science is being offered to the...
A Trump administration plan would expand the surveillance state at the borders, with implications beyond immigration.
Tests on lungs from 1912 say disease may have existed 2,300 years ago. If correct, findings could have implications for maintaining long-neglected archives.
A genetic approach could circumvent the pitfalls associated with current antivenom synthesis techniques
They can do simple tasks, and one day might reproduce themselves
Yale doctors have developed a way to create vascular grafts from stem cells that are as strong as the original blood vessels they would replace. The
The ISSCR is updating its Guidelines for Stem Cell Research and Clinical Translation to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell Reports 14:1-6). As the science continues to advance, it raises important scientific, clinical, ethical, and societal issues for researchers, regulators, and funding agencies. The ISSCR believes the scientific community must address these challenges to est
The ISSCR is updating its Guidelines to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell Reports 14:1-6). As the science continues to advance, it raises important scientific, clinical, ethical, and societal issues for researchers, regulators, and funding agencies. The ISSCR believes the scientific community must address these challenges to establish parameters for research in this area.
/PRNewswire/ -- Eric Hobbs, Ph.D., CEO of Berkeley Lights, spoke at the annual J.P. Morgan Healthcare Conference on Tuesday to a fully-packed room of industry...
A UC San Francisco-led research team has discovered the first conclusive evidence that selection may also occur at the level of the epigenome -- a term that refers to an assortment of chemical ''annotations'' to the genome that determine whether, when and to what extent genes are activated -- and has done so for tens of millions of years.
For the first time, research shows that the contacts between cells, known as cell adhesion, are essential for cells to survive stress. The findings also suggest that impaired cell adhesion may sensitize cancer cells to drugs that damage cell proteins and cause stress.
/PRNewswire/ -- Regen Suppliers announces the release of ReBella and ReBellaXO, umbilical stem cell and exosome products used for regenerative aesthetic...
A new study from Finland sheds fresh light on how melanoma cells interact with other cells via extracellular vesicles they secrete. The researchers found that extracellular vesicles secreted by melanoma cells use the so-called hedgehog signalling pathway to intensify the malignant properties of the cells they are targeting. The discovery can help in the development of better treatment and diagnostics for melanoma.
One of the most fascinating and important properties of living cells is their capacity for self-organization. By talking to each other, cells can, among other things, determine where they are in relation to each other and whether they need to turn certain genes on or off. Thus, large groups of cells are able to work together and organize into all kinds of tissues. Researchers at Delft University of Technology have now developed software that can predict and visualize conversations between cells
A woman's supply of eggs is finite, so it is crucial that the quality of their genetic material is ensured. New work from Carnegie's Marla Tharp, Safia Malki, and Alex Bortvin elucidates a mechanism by which, even before birth, the body tries to eliminate egg cells of the poorest quality.
They can move, carry loads, and repair themselves.